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Ablation of TRPC3 disrupts Ca(2+) signaling in salivary ductal cells and promotes sialolithiasis

Clinical studies and structural analyses of salivary stones strongly suggest a linkage between higher saliva calcium (Ca(2+)) and salivary stone formation, sialolithiasis; however, the process and the mechanism leading to Ca(2+) overload during sialolithiasis is not well understood. Here, we show th...

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Detalles Bibliográficos
Autores principales: Choi, Bok-Eum, Shin, Samuel, Evans, Sade, Singh, Brij B., Bandyopadhyay, Bidhan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082769/
https://www.ncbi.nlm.nih.gov/pubmed/37031239
http://dx.doi.org/10.1038/s41598-023-32602-8