PRPF19 facilitates colorectal cancer liver metastasis through activation of the Src-YAP1 pathway via K63-linked ubiquitination of MYL9

Distant metastasis is one of the leading causes of cancer-related mortality of colorectal cancer (CRC). Dysregulation of E3 ubiquitin ligases has been implicated in acting vital roles in multiple cancers. In this study, we found that the E3 ubiquitin ligase, PRPF19 was positively correlated with liv...

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Detalles Bibliográficos
Autores principales: Zhou, Rui, Chen, Jie, Xu, Yunxiuxiu, Ye, Yibiao, Zhong, Guoping, Chen, Tao, Qiu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082770/
https://www.ncbi.nlm.nih.gov/pubmed/37031206
http://dx.doi.org/10.1038/s41419-023-05776-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082770/
https://www.ncbi.nlm.nih.gov/pubmed/37031206
http://dx.doi.org/10.1038/s41419-023-05776-2

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