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Circulating blood eNAMPT drives the circadian rhythms in locomotor activity and energy expenditure

Nicotinamide adenine dinucleotide (NAD(+)) is an essential cofactor of critical enzymes including protein deacetylase sirtuins/SIRTs and its levels in mammalian cells rely on the nicotinamide phosphoribosyltransferase (NAMPT)-mediated salvage pathway. Intracellular NAMPT (iNAMPT) is secreted and fou...

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Detalles Bibliográficos
Autores principales: Park, Jae Woo, Roh, Eun, Kang, Gil Myoung, Gil, So Young, Kim, Hyun Kyong, Lee, Chan Hee, Jang, Won Hee, Park, Se Eun, Moon, Sang Yun, Kim, Seong Jun, Jeong, So Yeon, Park, Chae Beom, Lim, Hyo Sun, Oh, Yu Rim, Jung, Han Na, Kwon, Obin, Youn, Byung Soo, Son, Gi Hoon, Min, Se Hee, Kim, Min-Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082796/
https://www.ncbi.nlm.nih.gov/pubmed/37031230
http://dx.doi.org/10.1038/s41467-023-37517-6