Cargando…

Impact of porous microsponges in minimizing myotoxic side effects of simvastatin

Simvastatin (SV) is a poorly soluble drug; its oral administration is associated with a significant problem: Myopathy. The present study aims to formulate SV microsponges that have the potential to minimize the myotoxicity accompanying the oral administration of the drug. SV microsponges were prepar...

Descripción completa

Detalles Bibliográficos
Autores principales: Ali, Ahmed U., Abd-Elkareem, Mahmoud, Kamel, Amira A., Abou Khalil, Nasser S., Hamad, D., Nasr, Nasr Eldin Hussein, Hassan, Maha A., El Faham, Tahani H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082807/
https://www.ncbi.nlm.nih.gov/pubmed/37031209
http://dx.doi.org/10.1038/s41598-023-32545-0