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The problem of selection bias in studies of pre-mRNA splicing
Here we demonstrate how selection bias in studies of pre-mRNA splicing can inadvertently lead to inaccurate biological conclusions which nevertheless appear statistically robust. We argue that this may be a pervasive problem with potentially significant consequences for the field.
Autores principales: | Dwyer, Zachary W., Pleiss, Jeffrey A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082818/ https://www.ncbi.nlm.nih.gov/pubmed/37031238 http://dx.doi.org/10.1038/s41467-023-37650-2 |
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