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PLCG2 can exist in eccDNA and contribute to the metastasis of non-small cell lung cancer by regulating mitochondrial respiration

Extrachromosomal circular DNAs (eccDNAs) participate in tumorigenesis and tumor progression. However, the role and mechanism of eccDNAs have yet to be elucidated in non-small cell lung cancer (NSCLC). In our research, three surgically matched NSCLC tissue samples, NSCLC cell lines (H1299, A549, and...

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Detalles Bibliográficos
Autores principales: Yang, Yongfeng, Yang, Ying, Huang, Hong, Song, Tingting, Mao, Shengqiang, Liu, Dan, Zhang, Li, Li, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082821/
https://www.ncbi.nlm.nih.gov/pubmed/37031207
http://dx.doi.org/10.1038/s41419-023-05755-7