MOZ/ENL complex is a recruiting factor of leukemic AF10 fusion proteins

Changes in the transcriptional machinery cause aberrant self-renewal of non-stem hematopoietic progenitors. AF10 fusions, such as CALM-AF10, are generated via chromosomal translocations, causing malignant leukemia. In this study, we demonstrate that AF10 fusion proteins cause aberrant self-renewal v...

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Detalles Bibliográficos
Autores principales: Komata, Yosuke, Kanai, Akinori, Maeda, Takahiro, Inaba, Toshiya, Yokoyama, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082848/
https://www.ncbi.nlm.nih.gov/pubmed/37031220
http://dx.doi.org/10.1038/s41467-023-37712-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082848/
https://www.ncbi.nlm.nih.gov/pubmed/37031220
http://dx.doi.org/10.1038/s41467-023-37712-5

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