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Segmentation strategy of de novo designed four-helical bundles expands protein oligomerization modalities for cell regulation

Protein–protein interactions govern most biological processes. New protein assemblies can be introduced through the fusion of selected proteins with di/oligomerization domains, which interact specifically with their partners but not with other cellular proteins. While four-helical bundle proteins (4...

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Detalles Bibliográficos
Autores principales: Merljak, Estera, Malovrh, Benjamin, Jerala, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082849/
https://www.ncbi.nlm.nih.gov/pubmed/37031229
http://dx.doi.org/10.1038/s41467-023-37765-6