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Segmentation strategy of de novo designed four-helical bundles expands protein oligomerization modalities for cell regulation
Protein–protein interactions govern most biological processes. New protein assemblies can be introduced through the fusion of selected proteins with di/oligomerization domains, which interact specifically with their partners but not with other cellular proteins. While four-helical bundle proteins (4...
Autores principales: | Merljak, Estera, Malovrh, Benjamin, Jerala, Roman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082849/ https://www.ncbi.nlm.nih.gov/pubmed/37031229 http://dx.doi.org/10.1038/s41467-023-37765-6 |
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