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Myristate induces mitochondrial fragmentation and cardiomyocyte hypertrophy through mitochondrial E3 ubiquitin ligase MUL1

Introduction: Cardiovascular diseases, especially metabolic-related disorders, are progressively growing worldwide due to high-fat-containing foods, which promote a deleterious response at the cellular level, termed lipotoxicity, or lipotoxic stress. At the cardiac level, saturated fatty acids have...

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Detalles Bibliográficos
Autores principales: Vásquez-Trincado, César, Navarro-Márquez, Mario, Morales, Pablo E., Westermeier, Francisco, Chiong, Mario, Parra, Valentina, Espinosa, Alejandra, Lavandero, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083258/
https://www.ncbi.nlm.nih.gov/pubmed/37051468
http://dx.doi.org/10.3389/fcell.2023.1072315