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Assessment of the dual role of Lyonia ovalifolia (Wall.) Drude in inhibiting AGEs and enhancing GLUT4 translocation through LC-ESI-QTOF-MS/MS determination and in silico studies

Introduction: Diabetes mellitus (DM) is a metabolic disorder that results in glucose accumulation in the blood, accompanied by the production of advanced glycation end products (AGEs) through glycation of cellular proteins. These AGEs interfere with insulin signaling and prevent GLUT4 membrane trans...

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Detalles Bibliográficos
Autores principales: Sahu, Neha, Singh, Nitesh, Arya, Kamal Ram, Reddy, Sabbu Sathish, Rai, Amit Kumar, Shukla, Vijaya, Pandey, Jyotsana, Narender, Tadigoppula, Tamrakar, Akhilesh Kumar, Kumar, Brijesh, Rajak, Bikash Kumar, Malik, Sumira, Rustagi, Sarvesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083281/
https://www.ncbi.nlm.nih.gov/pubmed/37050897
http://dx.doi.org/10.3389/fphar.2023.1073327