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A male mouse model of WIN 55,212–2 self-administration to study cannabinoid addiction

We have established for the first time a mouse model of cannabinoid addiction using WIN 55,212–2 intravenous self-administration (0.0125 mg/kg/infusion) in C57Bl/6J mice. This model allows to evaluate the addiction criteria by grouping them into 1) persistence of response during a period of non-avai...

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Detalles Bibliográficos
Autores principales: Cajiao-Manrique, María del Mar, Maldonado, Rafael, Martín-García, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083303/
https://www.ncbi.nlm.nih.gov/pubmed/37050910
http://dx.doi.org/10.3389/fphar.2023.1143365