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Application of PCR-based approaches for evaluation of cell-free DNA fragmentation in colorectal cancer

Cell-free DNA (cfDNA) testing is the core of most liquid biopsy assays. In particular, cfDNA fragmentation features could facilitate non-invasive cancer detection due to their interconnection with tumor-specific epigenetic alterations. However, the final cfDNA fragmentation profile in a purified sam...

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Detalles Bibliográficos
Autores principales: Koval, Anastasia P., Khromova, Alexandra S., Blagodatskikh, Konstantin A., Zhitnyuk, Yulia V., Shtykova, Yanina A., Alferov, Aleksandr A., Kushlinskii, Nikolay E., Shcherbo, Dmitry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083340/
https://www.ncbi.nlm.nih.gov/pubmed/37051326
http://dx.doi.org/10.3389/fmolb.2023.1101179