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The genomic landscape of ANCA-associated vasculitis: Distinct transcriptional signatures, molecular endotypes and comparison with systemic lupus erythematosus

INTRODUCTION: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) present with a complex phenotype and are associated with high mortality and multi-organ involvement. We sought to define the transcriptional landscape and molecular endotypes of AAVs and compare it to systemic l...

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Detalles Bibliográficos
Autores principales: Banos, Aggelos, Thomas, Konstantinos, Garantziotis, Panagiotis, Filia, Anastasia, Malissovas, Nikolaos, Pieta, Antigone, Nikolakis, Dimitrios, Panagiotopoulos, Alexandros G., Chalkia, Aglaia, Petras, Dimitrios, Bertsias, George, Boumpas, Dimitrios T., Vassilopoulos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083368/
https://www.ncbi.nlm.nih.gov/pubmed/37051253
http://dx.doi.org/10.3389/fimmu.2023.1072598