Integrative epigenome profiling of 47XXY provides insights into whole genomic DNA hypermethylation and active chromatin accessibility

Klinefelter syndrome (KS, 47XXY) is a disorder characterized by sex chromosomal aneuploidy, which may lead to changes in epigenetic regulations of gene expression. To define epigenetic architectures in 47XXY, we annotated DNA methylation in euploid males (46XY) and females (46XX), and 47XXY individu...

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Detalles Bibliográficos
Autores principales: Miao, Nan, Zeng, Zhiwei, Lee, Trevor, Guo, Qiwei, Zheng, Wenwei, Cai, Wenjie, Chen, Wanhua, Wang, Jing, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083376/
https://www.ncbi.nlm.nih.gov/pubmed/37051325
http://dx.doi.org/10.3389/fmolb.2023.1128739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083376/
https://www.ncbi.nlm.nih.gov/pubmed/37051325
http://dx.doi.org/10.3389/fmolb.2023.1128739

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