Small molecules targeting Pin1 as potent anticancer drugs

Background: Pin1 is a member of the evolutionarily conserved peptidyl-prolyl isomerase (PPIase) family of proteins. Following phosphorylation, Pin1-catalyzed prolyl-isomerization induces conformational changes, which serve to regulate the function of many phosphorylated proteins that play important...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Zhang, Jing, Zhou, Wenwen, Chen, Yunyu, Wang, Yanchang, Guo, Zongru, Hu, Wenhui, Li, Yan, Han, Xiaomin, Si, Shuyi
Format: Online Artikel Text
Sprache:English
Veröffentlicht: Frontiers Media S.A. 2023
Schlagworte:
Pharmacology
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083437/
https://www.ncbi.nlm.nih.gov/pubmed/37050909
http://dx.doi.org/10.3389/fphar.2023.1073037

Online

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083437/
https://www.ncbi.nlm.nih.gov/pubmed/37050909
http://dx.doi.org/10.3389/fphar.2023.1073037

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