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Acetaminophen-induced liver injury: Molecular mechanism and treatments from natural products

Acetaminophen (APAP) is a widely used analgesic and antipyretic over-the-counter medicine worldwide. Hepatotoxicity caused by APAP overdose is one of the leading causes of acute liver failure (ALF) in the US and in some parts of Europe, limiting its clinical application. Excessive APAP metabolism de...

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Detalles Bibliográficos
Autores principales: Liao, Jiaqing, Lu, Qiuxia, Li, Zhiqi, Li, Jintao, Zhao, Qi, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083499/
https://www.ncbi.nlm.nih.gov/pubmed/37050900
http://dx.doi.org/10.3389/fphar.2023.1122632