Statins enhance the efficacy of HER2-targeting radioligand therapy in drug-resistant gastric cancers

Human epidermal growth factor receptor 2 (HER2) is overexpressed in various cancer types. HER2-targeting trastuzumab plus chemotherapy is used as first-line therapy for HER2-positive recurrent or primary metastatic gastric cancer, but intrinsic and acquired trastuzumab resistance inevitably develop...

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Detalles Bibliográficos
Autores principales: Rao, Yi, Samuels, Zachary, Carter, Lukas M., Monette, Sebastien, Panikar, Sandeep Surendra, Pereira, Patricia M. R., Lewis, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083538/
https://www.ncbi.nlm.nih.gov/pubmed/36972439
http://dx.doi.org/10.1073/pnas.2220413120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083538/
https://www.ncbi.nlm.nih.gov/pubmed/36972439
http://dx.doi.org/10.1073/pnas.2220413120

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