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Statins enhance the efficacy of HER2-targeting radioligand therapy in drug-resistant gastric cancers
Human epidermal growth factor receptor 2 (HER2) is overexpressed in various cancer types. HER2-targeting trastuzumab plus chemotherapy is used as first-line therapy for HER2-positive recurrent or primary metastatic gastric cancer, but intrinsic and acquired trastuzumab resistance inevitably develop...
Autores principales: | Rao, Yi, Samuels, Zachary, Carter, Lukas M., Monette, Sebastien, Panikar, Sandeep Surendra, Pereira, Patricia M. R., Lewis, Jason S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083538/ https://www.ncbi.nlm.nih.gov/pubmed/36972439 http://dx.doi.org/10.1073/pnas.2220413120 |
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