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Allosteric inactivation of an engineered optogenetic GTPase

Optogenetics is a technique for establishing direct spatiotemporal control over molecular function within living cells using light. Light application induces conformational changes within targeted proteins that produce changes in function. One of the applications of optogenetic tools is an allosteri...

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Detalles Bibliográficos
Autores principales: Jain, Abha, Dokholyan, Nikolay V., Lee, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083549/
https://www.ncbi.nlm.nih.gov/pubmed/36972433
http://dx.doi.org/10.1073/pnas.2219254120