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A general mechanism for transcription bubble nucleation in bacteria
Bacterial transcription initiation requires σ factors for nucleation of the transcription bubble. The canonical housekeeping σ factor, σ(70), nucleates DNA melting via recognition of conserved bases of the promoter −10 motif, which are unstacked and captured in pockets of σ(70). By contrast, the mec...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083551/ https://www.ncbi.nlm.nih.gov/pubmed/36972428 http://dx.doi.org/10.1073/pnas.2220874120 |