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Treg cells require Izumo1R to regulate γδT cell-driven inflammation in the skin

Izumo1R is a pseudo-folate receptor with an essential role in mediating tight oocyte/spermatozoa contacts during fertilization. Intriguingly, it is also expressed in CD4(+) T lymphocytes, in particular Treg cells under the control of Foxp3. To understand Izumo1R function in Treg cells, we analyzed m...

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Detalles Bibliográficos
Autores principales: Zarin, Payam, Shwartz, Yulia, Ortiz-Lopez, Adriana, Hanna, Bola S., Sassone-Corsi, Martina, Hsu, Ya-chieh, Mathis, Diane, Benoist, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083566/
https://www.ncbi.nlm.nih.gov/pubmed/36972453
http://dx.doi.org/10.1073/pnas.2221255120