microRNA-449a reduces growth hormone-stimulated senescent cell burden through PI3K-mTOR signaling

Cellular senescence, a hallmark of aging, has been implicated in the pathogenesis of many major age-related disorders, including neurodegeneration, atherosclerosis, and metabolic disease. Therefore, investigating novel methods to reduce or delay the accumulation of senescent cells during aging may a...

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Detalles Bibliográficos
Autores principales: Noureddine, Sarah, Nie, Jia, Schneider, Augusto, Menon, Vinal, Fliesen, Zoubeida, Dhahbi, Joseph, Victoria, Berta, Oyer, Jeremiah, Robles-Carrillo, Liza, Nunes, Allancer Divino De Carvalho, Ashiqueali, Sarah, Janusz, Artur, Copik, Alicja, Robbins, Paul D., Musi, Nicolas, Masternak, Michal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083567/
https://www.ncbi.nlm.nih.gov/pubmed/36976763
http://dx.doi.org/10.1073/pnas.2213207120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083567/
https://www.ncbi.nlm.nih.gov/pubmed/36976763
http://dx.doi.org/10.1073/pnas.2213207120

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