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microRNA-449a reduces growth hormone-stimulated senescent cell burden through PI3K-mTOR signaling
Cellular senescence, a hallmark of aging, has been implicated in the pathogenesis of many major age-related disorders, including neurodegeneration, atherosclerosis, and metabolic disease. Therefore, investigating novel methods to reduce or delay the accumulation of senescent cells during aging may a...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083567/ https://www.ncbi.nlm.nih.gov/pubmed/36976763 http://dx.doi.org/10.1073/pnas.2213207120 |