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Identification of a broadly conserved family of enzymes that hydrolyze (p)ppApp
Bacteria produce a variety of nucleotide second messengers to adapt to their surroundings. Although chemically similar, the nucleotides guanosine penta- and tetraphosphate [(p)ppGpp] and adenosine penta- and tetraphosphate [(p)ppApp] have distinct functions in bacteria. (p)ppGpp mediates survival un...
Autores principales: | Ahmad, Shehryar, Gordon, Isis J., Tsang, Kara K., Alexei, Andrea G., Sychantha, David, Colautti, Jake, Trilesky, Sarah L., Kim, Youngchang, Wang, Boyuan, Whitney, John C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083569/ https://www.ncbi.nlm.nih.gov/pubmed/36989297 http://dx.doi.org/10.1073/pnas.2213771120 |
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