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Immunoglobulin G subclasses confer protection against Staphylococcus aureus bloodstream dissemination through distinct mechanisms in mouse models

Antibodies bind target molecules with exquisite specificity. The removal of these targets is mediated by the effector functions of antibodies. We reported earlier that the monoclonal antibody (mAb) 3F6 promotes opsonophagocytic killing of Staphylococcus aureus in blood and reduces bacterial replicat...

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Detalles Bibliográficos
Autores principales: Chen, Xinhai, Gula, Haley, Pius, Tonu, Ou, Chong, Gomozkova, Margaryta, Wang, Lai-Xi, Schneewind, Olaf, Missiakas, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083571/
https://www.ncbi.nlm.nih.gov/pubmed/36972444
http://dx.doi.org/10.1073/pnas.2220765120