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Neuronal activity-induced, equilibrative nucleoside transporter-dependent, somatodendritic adenosine release revealed by a GRAB sensor

The purinergic signaling molecule adenosine (Ado) modulates many physiological and pathological functions in the brain. However, the exact source of extracellular Ado remains controversial. Here, utilizing a newly optimized genetically encoded GPCR-Activation-Based Ado fluorescent sensor (GRAB(Ado))...

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Detalles Bibliográficos
Autores principales: Wu, Zhaofa, Cui, Yuting, Wang, Huan, Wu, Hao, Wan, Yi, Li, Bohan, Wang, Lei, Pan, Sunlei, Peng, Wanling, Dong, Ao, Yuan, Zhengwei, Jing, Miao, Xu, Min, Luo, Minmin, Li, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083574/
https://www.ncbi.nlm.nih.gov/pubmed/36996110
http://dx.doi.org/10.1073/pnas.2212387120