NAMPT-dependent NAD(+) biosynthesis controls circadian metabolism in a tissue-specific manner

Molecular clocks in the periphery coordinate tissue-specific daily biorhythms by integrating input from the hypothalamic master clock and intracellular metabolic signals. One such key metabolic signal is the cellular concentration of NAD(+), which oscillates along with its biosynthetic enzyme, nicot...

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Detalles Bibliográficos
Autores principales: Basse, Astrid L., Nielsen, Karen N., Karavaeva, Iuliia, Ingerslev, Lars R., Ma, Tao, Havelund, Jesper F., Nielsen, Thomas S., Frost, Mikkel, Peics, Julia, Dalbram, Emilie, Dall, Morten, Zierath, Juleen R., Barrès, Romain, Færgeman, Nils J., Treebak, Jonas T., Gerhart-Hines, Zachary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083581/
https://www.ncbi.nlm.nih.gov/pubmed/36996103
http://dx.doi.org/10.1073/pnas.2220102120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083581/
https://www.ncbi.nlm.nih.gov/pubmed/36996103
http://dx.doi.org/10.1073/pnas.2220102120

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