Structural insights into constitutive activity of 5-HT(6) receptor

While most therapeutic research on G-protein-coupled receptors (GPCRs) focuses on receptor activation by (endogenous) agonists, significant therapeutic potential exists through agonist-independent intrinsic constitutive activity that can occur in various physiological and pathophysiological settings...

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Detalles Bibliográficos
Autores principales: He, Licong, Zhao, Qiaoyu, Qi, Jianzhong, Wang, Yifan, Han, Wenyu, Chen, Zhangcheng, Cong, Yao, Wang, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083584/
https://www.ncbi.nlm.nih.gov/pubmed/36989299
http://dx.doi.org/10.1073/pnas.2209917120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083584/
https://www.ncbi.nlm.nih.gov/pubmed/36989299
http://dx.doi.org/10.1073/pnas.2209917120

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