Acute phosphatidylinositol 4,5 bisphosphate depletion destabilizes sarcolemmal expression of cardiac L-type Ca(2+) channel Ca(V)1.2

Ca(V)1.2 channels are critical players in cardiac excitation–contraction coupling, yet we do not understand how they are affected by an important therapeutic target of heart failure drugs and regulator of blood pressure, angiotensin II. Signaling through G(q)-coupled AT1 receptors, angiotensin II tr...

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Detalles Bibliográficos
Autores principales: Voelker, Taylor L., del Villar, Silvia G., Westhoff, Maartje, Costa, Alexandre D., Coleman, Andrea M., Hell, Johannes W., Horne, Mary C., Dickson, Eamonn J., Dixon, Rose E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083594/
https://www.ncbi.nlm.nih.gov/pubmed/36976770
http://dx.doi.org/10.1073/pnas.2221242120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083594/
https://www.ncbi.nlm.nih.gov/pubmed/36976770
http://dx.doi.org/10.1073/pnas.2221242120

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