Epitranscriptic regulation of HRAS by N(6)-methyladenosine drives tumor progression

Overexpression of Ras, in addition to the oncogenic mutations, occurs in various human cancers. However, the mechanisms for epitranscriptic regulation of RAS in tumorigenesis remain unclear. Here, we report that the widespread N(6)-methyladenosine (m(6)A) modification of HRAS, but not KRAS and NRAS,...

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Detalles Bibliográficos
Autores principales: Pan, Yongbo, Gu, Yinmin, Liu, Tihui, Zhang, Qingqing, Yang, Facai, Duan, Liqiang, Cheng, Shuwen, Zhu, Xiaofeng, Xi, Yibo, Chang, Xiaoli, Ye, Qinong, Gao, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083612/
https://www.ncbi.nlm.nih.gov/pubmed/36996116
http://dx.doi.org/10.1073/pnas.2302291120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083612/
https://www.ncbi.nlm.nih.gov/pubmed/36996116
http://dx.doi.org/10.1073/pnas.2302291120

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