NEDD4L facilitates granulosa cell ferroptosis by promoting GPX4 ubiquitination and degradation

BACKGROUND: Polycystic ovary syndrome (PCOS) is an androgen disorder and ovarian dysfunction disease in women of reproductive age. The cell death of granulosa cells (GCs) plays an important role in the development of PCOS. However, the mechanism of GC death is still unclear. METHODS: In the current...

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Detalles Bibliográficos
Autores principales: Tang, Hong, Jiang, Xiaomei, Hua, Yu, Li, Heyue, Zhu, Chunlan, Hao, Xiaobai, Yi, Minhui, Li, Linxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083675/
https://www.ncbi.nlm.nih.gov/pubmed/36662677
http://dx.doi.org/10.1530/EC-22-0459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083675/
https://www.ncbi.nlm.nih.gov/pubmed/36662677
http://dx.doi.org/10.1530/EC-22-0459

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