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NEDD4L facilitates granulosa cell ferroptosis by promoting GPX4 ubiquitination and degradation
BACKGROUND: Polycystic ovary syndrome (PCOS) is an androgen disorder and ovarian dysfunction disease in women of reproductive age. The cell death of granulosa cells (GCs) plays an important role in the development of PCOS. However, the mechanism of GC death is still unclear. METHODS: In the current...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Bioscientifica Ltd
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083675/ https://www.ncbi.nlm.nih.gov/pubmed/36662677 http://dx.doi.org/10.1530/EC-22-0459 |