Cargando…

Kinetics of the thapsigargin-induced Ca(2+) mobilisation: A quantitative analysis in the HEK-293 cell line

Thapsigargin (TG) inhibits the sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) pump and, when applied acutely, it initiates a Ca(2+) mobilisation that begins with the loss of Ca(2+) from the endoplasmic reticulum (ER) and culminates with store-operated Ca(2+) entry (SOCE) from the extracellular sp...

Descripción completa

Detalles Bibliográficos
Autores principales: Pick, Tillman, Gamayun, Igor, Tinschert, René, Cavalié, Adolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083721/
https://www.ncbi.nlm.nih.gov/pubmed/37051019
http://dx.doi.org/10.3389/fphys.2023.1127545