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Kinetics of the thapsigargin-induced Ca(2+) mobilisation: A quantitative analysis in the HEK-293 cell line
Thapsigargin (TG) inhibits the sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) pump and, when applied acutely, it initiates a Ca(2+) mobilisation that begins with the loss of Ca(2+) from the endoplasmic reticulum (ER) and culminates with store-operated Ca(2+) entry (SOCE) from the extracellular sp...
Autores principales: | Pick, Tillman, Gamayun, Igor, Tinschert, René, Cavalié, Adolfo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083721/ https://www.ncbi.nlm.nih.gov/pubmed/37051019 http://dx.doi.org/10.3389/fphys.2023.1127545 |
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