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LDH as an adjuvant makes Brucella outer-membrane vesicles and outer-membrane vesicle-associated proteins highly protective in mice

OBJECTIVE(S): Existing Brucella vaccines are attenuated and can cause vaccine-associated brucellosis; and these safety concerns have affected their application. Although subunit vaccines have the advantages of safety, efficacy, low cost, and rapid production, they are usually poorly immunogenic and...

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Detalles Bibliográficos
Autores principales: Deng, Xiaoyu, He, Jinke, Xu, Jinfeng, Wang, Yueli, Yi, Jihai, Zhang, Huan, Wang, Yong, Wang, Zhen, Chen, Chuangfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083835/
https://www.ncbi.nlm.nih.gov/pubmed/37051103
http://dx.doi.org/10.22038/IJBMS.2023.67394.14775