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LDH as an adjuvant makes Brucella outer-membrane vesicles and outer-membrane vesicle-associated proteins highly protective in mice
OBJECTIVE(S): Existing Brucella vaccines are attenuated and can cause vaccine-associated brucellosis; and these safety concerns have affected their application. Although subunit vaccines have the advantages of safety, efficacy, low cost, and rapid production, they are usually poorly immunogenic and...
Autores principales: | Deng, Xiaoyu, He, Jinke, Xu, Jinfeng, Wang, Yueli, Yi, Jihai, Zhang, Huan, Wang, Yong, Wang, Zhen, Chen, Chuangfu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083835/ https://www.ncbi.nlm.nih.gov/pubmed/37051103 http://dx.doi.org/10.22038/IJBMS.2023.67394.14775 |
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