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Development of the oncolytic virus, CF33, and its derivatives for peritoneal-directed treatment of gastric cancer peritoneal metastases

BACKGROUND: Gastric cancer (GC) that metastasizes to the peritoneum is fatal. CF33 and its genetically modified derivatives show cancer selectivity and oncolytic potency against various solid tumors. CF33-hNIS and CF33-hNIS-antiPDL1 have entered phase I trials for intratumoral and intravenous treatm...

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Detalles Bibliográficos
Autores principales: Yang, Annie, Zhang, Zhifang, Chaurasiya, Shyambabu, Park, Anthony K, Jung, Audrey, Lu, Jianming, Kim, Sang-In, Priceman, Saul, Fong, Yuman, Woo, Yanghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083877/
https://www.ncbi.nlm.nih.gov/pubmed/37019471
http://dx.doi.org/10.1136/jitc-2022-006280