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Ubiquitin-Specific Protease 43 Impacts Pancreatic Ductal Adenocarcinoma Prognosis by Altering Its Proliferation and Infiltration of Surrounding Immune Cells

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a devastating cancer, and the therapy options for PDAC remain restricted. The distinctive tumor immunological microenvironment (TIME) of PDAC, comprising a high number of stromal cells and a limited infiltration of cytotoxic T lymphocytes (CTLs)...

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Detalles Bibliográficos
Autores principales: Zhao, Ziqi, Lin, Zhikun, Guo, Xin, Al-danakh, Abdullah, He, Hui, Qin, Henan, Ma, Chi, Zhang, Ningning, Tan, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083889/
https://www.ncbi.nlm.nih.gov/pubmed/37050932
http://dx.doi.org/10.1155/2023/4311388