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Effects of glepaglutide, a long‐acting glucagon‐like peptide‐2 analog, on intestinal morphology and perfusion in patients with short bowel syndrome: Findings from a randomized phase 2 trial

BACKGROUND: The proadaptive effects of glucagon‐like peptide‐2 (GLP‐2) include stimulation of intestinal mucosal growth as well as intestinal blood flow and angiogenesis. We have recently reported that daily subcutaneous injections of glepaglutide, a long‐acting GLP‐2 analog, improved intestinal abs...

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Detalles Bibliográficos
Autores principales: Naimi, Rahim M., Hvistendahl, Mark K., Poulsen, Steen S., Kissow, Hannelouise, Pedersen, Jens, Nerup, Nikolaj A., Ambrus, Rikard, Achiam, Michael P., Svendsen, Lars B., Jeppesen, Palle B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084040/
https://www.ncbi.nlm.nih.gov/pubmed/35511704
http://dx.doi.org/10.1002/jpen.2389