Celecoxib‐tramadol co‐crystal in patients with moderate‐to‐severe pain following bunionectomy with osteotomy: A phase 3, randomized, double‐blind, factorial, active‐ and placebo‐controlled trial

BACKGROUND: Celecoxib‐tramadol co‐crystal (CTC) is a first‐in‐class analgesic co‐crystal of celecoxib and racemic tramadol with an improved pharmacologic profile, conferred by the co‐crystal structure, compared with its active constituents administered alone/concomitantly. AIM: We evaluated CTC in m...

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Detalles Bibliográficos
Autores principales: Viscusi, Eugene R., de Leon‐Casasola, Oscar, Cebrecos, Jesús, Jacobs, Adam, Morte, Adelaida, Ortiz, Esther, Sust, Mariano, Vaqué, Anna, Gottlieb, Ira, Daniels, Stephen, Gimbel, Joseph S., Muse, Derek, Winkle, Peter, Kuss, Michael E., Videla, Sebastián, Gascón, Neus, Plata‐Salamán, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084286/
https://www.ncbi.nlm.nih.gov/pubmed/35686380
http://dx.doi.org/10.1111/papr.13136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084286/
https://www.ncbi.nlm.nih.gov/pubmed/35686380
http://dx.doi.org/10.1111/papr.13136

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