Cargando…

Celecoxib‐tramadol co‐crystal in patients with moderate‐to‐severe pain following bunionectomy with osteotomy: A phase 3, randomized, double‐blind, factorial, active‐ and placebo‐controlled trial

BACKGROUND: Celecoxib‐tramadol co‐crystal (CTC) is a first‐in‐class analgesic co‐crystal of celecoxib and racemic tramadol with an improved pharmacologic profile, conferred by the co‐crystal structure, compared with its active constituents administered alone/concomitantly. AIM: We evaluated CTC in m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Viscusi, Eugene R., de Leon‐Casasola, Oscar, Cebrecos, Jesús, Jacobs, Adam, Morte, Adelaida, Ortiz, Esther, Sust, Mariano, Vaqué, Anna, Gottlieb, Ira, Daniels, Stephen, Gimbel, Joseph S., Muse, Derek, Winkle, Peter, Kuss, Michael E., Videla, Sebastián, Gascón, Neus, Plata‐Salamán, Carlos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084286/ https://www.ncbi.nlm.nih.gov/pubmed/35686380 http://dx.doi.org/10.1111/papr.13136

Ejemplares similares

Efficacy and safety of co‐crystal of tramadol‐celecoxib (CTC) in acute moderate‐to‐severe pain after abdominal hysterectomy: A randomized, double‐blind, phase 3 trial (STARDOM2)
por: Langford, Richard, et al.
Publicado: (2022)

Pharmacokinetics of multiple doses of co‐crystal of tramadol–celecoxib: findings from a four‐way randomized open‐label phase I clinical trial
por: Videla, Sebastián, et al.
Publicado: (2017)

Single‐dose pharmacokinetics of co‐crystal of tramadol–celecoxib: Results of a four‐way randomized open‐label phase I clinical trial in healthy subjects
por: Videla, Sebastián, et al.
Publicado: (2017)

The Effect of Food on Tramadol and Celecoxib Bioavailability Following Oral Administration of Co-Crystal of Tramadol–Celecoxib (CTC): A Randomised, Open-Label, Single-Dose, Crossover Study in Healthy Volunteers
por: Encina, Gregorio, et al.
Publicado: (2018)

Co-crystal of Tramadol–Celecoxib in Patients with Moderate to Severe Acute Post-surgical Oral Pain: A Dose-Finding, Randomised, Double-Blind, Placebo- and Active-Controlled, Multicentre, Phase II Trial
por: López-Cedrún, José, et al.
Publicado: (2018)

Efficacy and Safety of Intravenously Administered Tramadol in Patients with Moderate to Severe Pain Following Bunionectomy: A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study
por: Singla, Neil K., et al.
Publicado: (2020)

Evaluation of the safety and efficacy of an intravenous nanocrystal formulation of meloxicam in the management of moderate-to-severe pain after bunionectomy
por: Gottlieb, Ira J, et al.
Publicado: (2018)

Pharmacokinetics of Tramadol and Celecoxib in Japanese and Caucasian Subjects Following Administration of Co-Crystal of Tramadol-Celecoxib (CTC): A Randomised, Open-Label Study
por: Dooner, Helen, et al.
Publicado: (2018)

Celecoxib-tramadol co-crystal: Efficacy in acute postoperative pain
por: Nair, Abhijit Sukumaran
Publicado: (2022)

Radiographic Forefoot Width Following Minimally Invasive Chevron Akin Bunionectomy
por: Klavas, Derek M., et al.
Publicado: (2023)

Analgesic Efficacy and Safety of Tapentadol Immediate Release in Bunionectomy: A Meta-Analysis
por: Franco-de la Torre, Lorenzo, et al.
Publicado: (2023)

Efficacy of a Novel Sigma-1 Receptor Antagonist for Oxaliplatin-Induced Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Clinical Trial
por: Bruna, Jordi, et al.
Publicado: (2017)

Clinical and Radiographic Outcomes of Minimally Invasive Chevron Bunionectomy Compared to the Modified Lapidus Procedure
por: Cody, Elizabeth, et al.
Publicado: (2022)

Early Radiographic Outcomes of Minimally Invasive Chevron Bunionectomy Compared to the Modified Lapidus Procedure
por: Cody, Elizabeth A., et al.
Publicado: (2022)

Tramadol withdrawal psychosis
por: Sidana, Ajeet, et al.
Publicado: (2019)

APOLLO-1: a randomized placebo and active-controlled phase III study investigating oliceridine (TRV130), a G protein-biased ligand at the µ-opioid receptor, for management of moderate-to-severe acute pain following bunionectomy
por: Viscusi, Eugene R, et al.
Publicado: (2019)

Severe cast burn after bunionectomy in a patient who received peripheral nerve blocks for postoperative analgesia
por: Boyle, Patrick K, et al.
Publicado: (2011)

Assessment of rescue opioid use in patients with post-bunionectomy pain treated with diclofenac potassium liquid-filled capsules
por: Willens, Joyce S, et al.
Publicado: (2015)

Eco-friendly simultaneous multi-spectrophotometric estimation of the newly approved drug combination of celecoxib and tramadol hydrochloride tablets in its dosage form
por: Ramadan, Hesham Sameh, et al.
Publicado: (2023)

First-in-human randomized clinical trials of the safety and efficacy of tanezumab for treatment of chronic knee osteoarthritis pain or acute bunionectomy pain
por: Walicke, Patricia A., et al.
Publicado: (2018)

A Comparison of Cardiovascular Biomarkers in Patients Treated for Three Months with Etoricoxib, Celecoxib, Ibuprofen, and Placebo
por: Cannon, Christopher P, et al.
Publicado: (2008)

Cytokinesis-block micronucleus assay of celecoxib and celecoxib derivatives
por: Reimann, Hauke, et al.
Publicado: (2020)

Tramadol : 15 años en México
Publicado: (2006)

Tramadol: Various toxicities following accidental tramadol poisoning: case report
Publicado: (2022)

Comparative Bioavailability Study of a Novel Multi-Day Patch Formulation of Rivastigmine (Twice Weekly) with Exelon(®) Transdermal Patch (Daily)- A Randomized Clinical Trial
por: Schurad, Bjoern, et al.
Publicado: (2022)

Tramadol and Sexual Dysfunction
por: Err, Hai, et al.
Publicado: (2015)

Tramadol Induced Jerks
por: Wasey, Waiz, et al.
Publicado: (2021)

Celecoxib Analogues for Cancer Treatment: An Update on OSU-03012 and 2,5-Dimethyl-Celecoxib
por: Sobolewski, Cyril, et al.
Publicado: (2021)

Molecular Network-Based Identification of Tramadol Metabolites in a Fatal Tramadol Poisoning
por: Magny, Romain, et al.
Publicado: (2022)

A Phase 3, Randomized, Double-Blind Comparison of Analgesic Efficacy and Tolerability of Q8003 vs Oxycodone or Morphine for Moderate-to-Severe Postoperative Pain Following Bunionectomy Surgery
por: Richards, Patricia, et al.
Publicado: (2013)

Challenges and Opportunities for Celecoxib Repurposing
por: Bąk, Urszula, et al.
Publicado: (2023)

A New Pharmacophore Model for the Design of Sigma-1 Ligands Validated on a Large Experimental Dataset
por: Pascual, Rosalia, et al.
Publicado: (2019)

Preparation and Evaluation of Amino Acid Conjugates of Celecoxib as Prodrugs to Improve the Pharmacokinetic and Therapeutic Properties of Celecoxib
por: Lee, Yonghyun, et al.
Publicado: (2020)

Uptake/Efflux Transport of Tramadol Enantiomers and O-Desmethyl-Tramadol: Focus on P-Glycoprotein
por: Kanaan, Mouna, et al.
Publicado: (2009)

Comparative study of the analgesic efficacy of rectal tramadol versus intravenous tramadol for adult tonsillectomy
por: Gadani, Hina N., et al.
Publicado: (2010)

HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in herniorrhaphy: results from the phase 3 EPOCH 2 study
por: Viscusi, E., et al.
Publicado: (2019)

Tramadol toxicity-induced rhabdomyolysis
por: Yousef Khan, Fahmi, et al.
Publicado: (2010)

Urinary Incontinence Induced by Tramadol
por: Gautam, Sujeet KS, et al.
Publicado: (2013)

Psychosis following Tramadol Withdrawal
por: Rajabizadeh, Ghodratolah, et al.
Publicado: (2009)

Tramadol: Delirium: case report
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_so6rnj913ksdpjvkfr4kqnjcbf