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Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups

INTRODUCTION: While complement is a contributor to disease severity in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, all three complement pathways might be activated by the virus. Lectin pathway activation occurs through different pattern recognition molecules, including m...

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Detalles Bibliográficos
Autores principales: Hurler, Lisa, Szilágyi, Ágnes, Mescia, Federica, Bergamaschi, Laura, Mező, Blanka, Sinkovits, György, Réti, Marienn, Müller, Veronika, Iványi, Zsolt, Gál, János, Gopcsa, László, Reményi, Péter, Szathmáry, Beáta, Lakatos, Botond, Szlávik, János, Bobek, Ilona, Prohászka, Zita Z., Förhécz, Zsolt, Csuka, Dorottya, Kajdácsi, Erika, Cervenak, László, Kiszel, Petra, Masszi, Tamás, Vályi-Nagy, István, Würzner, Reinhard, Lyons, Paul A., Toonen, Erik J. M., Prohászka, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084477/
https://www.ncbi.nlm.nih.gov/pubmed/37051252
http://dx.doi.org/10.3389/fimmu.2023.1162171