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Elevated ZNF704 expression is associated with poor prognosis of uveal melanoma and promotes cancer cell growth by regulating AKT/mTOR signaling

BACKGROUND: Uveal melanoma (UM) is the most common intraocular malignancy in adults, with a poor survival prognosis. To date, limited understanding of UM’s molecular mechanisms constitutes an obstacle to developing effective therapy. In this study, we examined key regulators mediating UM progression...

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Detalles Bibliográficos
Autores principales: Luo, Jingting, Li, Haowen, Xiu, Jingying, Zeng, Jingyao, Feng, Zhaoxun, Zhao, Hanqing, Li, Yang, Wei, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084591/
https://www.ncbi.nlm.nih.gov/pubmed/37038184
http://dx.doi.org/10.1186/s40364-023-00471-y