Cargando…

Plasma NfL is associated with the APOE ε4 allele, brain imaging measurements of neurodegeneration, and lower recall memory scores in cognitively unimpaired late-middle-aged and older adults

BACKGROUND: Plasma neurofilament light (NfL) is an indicator of neurodegeneration and/or neuroaxonal injury in persons with Alzheimer’s disease (AD) and a wide range of other neurological disorders. Here, we characterized and compared plasma NfL concentrations in cognitively unimpaired (CU) late-mid...

Descripción completa

Detalles Bibliográficos
Autores principales: Malek-Ahmadi, Michael, Su, Yi, Ghisays, Valentina, Luo, Ji, Devadas, Vivek, Chen, Yinghua, Lee, Wendy, Protas, Hillary, Chen, Kewei, Zetterberg, Henrik, Blennow, Kaj, Caselli, Richard J., Reiman, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084600/
https://www.ncbi.nlm.nih.gov/pubmed/37038190
http://dx.doi.org/10.1186/s13195-023-01221-w