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Plasma NfL is associated with the APOE ε4 allele, brain imaging measurements of neurodegeneration, and lower recall memory scores in cognitively unimpaired late-middle-aged and older adults
BACKGROUND: Plasma neurofilament light (NfL) is an indicator of neurodegeneration and/or neuroaxonal injury in persons with Alzheimer’s disease (AD) and a wide range of other neurological disorders. Here, we characterized and compared plasma NfL concentrations in cognitively unimpaired (CU) late-mid...
Autores principales: | Malek-Ahmadi, Michael, Su, Yi, Ghisays, Valentina, Luo, Ji, Devadas, Vivek, Chen, Yinghua, Lee, Wendy, Protas, Hillary, Chen, Kewei, Zetterberg, Henrik, Blennow, Kaj, Caselli, Richard J., Reiman, Eric M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084600/ https://www.ncbi.nlm.nih.gov/pubmed/37038190 http://dx.doi.org/10.1186/s13195-023-01221-w |
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