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Genome-wide association testing in malaria studies in the presence of overdominance

BACKGROUND: In human genetics, heterozygote advantage (heterosis) has been detected in studies that focused on specific genes but not in genome-wide association studies (GWAS). For example, heterosis is believed to confer resistance to certain strains of malaria in patients heterozygous for the sick...

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Detalles Bibliográficos
Autores principales:	Akoth, Morine, Odhiambo, John, Omolo, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084622/ https://www.ncbi.nlm.nih.gov/pubmed/37038187 http://dx.doi.org/10.1186/s12936-023-04533-2

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