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Super-enhancer-driven TOX2 mediates oncogenesis in Natural Killer/T Cell Lymphoma
BACKGROUND: Extranodal natural killer/T-cell lymphoma (NKTL) is an aggressive type of non-Hodgkin lymphoma with dismal outcome. A better understanding of disease biology and key oncogenic process is necessary for the development of targeted therapy. Super-enhancers (SEs) have been shown to drive piv...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084643/ https://www.ncbi.nlm.nih.gov/pubmed/37032358 http://dx.doi.org/10.1186/s12943-023-01767-1 |