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Super-enhancer-driven TOX2 mediates oncogenesis in Natural Killer/T Cell Lymphoma

BACKGROUND: Extranodal natural killer/T-cell lymphoma (NKTL) is an aggressive type of non-Hodgkin lymphoma with dismal outcome. A better understanding of disease biology and key oncogenic process is necessary for the development of targeted therapy. Super-enhancers (SEs) have been shown to drive piv...

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Detalles Bibliográficos
Autores principales:	Zhou, Jianbiao, Toh, Sabrina Hui-Min, Tan, Tze King, Balan, Kalpnaa, Lim, Jing Quan, Tan, Tuan Zea, Xiong, Sinan, Jia, Yunlu, Ng, Siok-Bian, Peng, Yanfen, Jeyasekharan, Anand D., Fan, Shuangyi, Lim, Soon Thye, Ong, Chin-Ann Johnny, Ong, Choon Kiat, Sanda, Takaomi, Chng, Wee-Joo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084643/ https://www.ncbi.nlm.nih.gov/pubmed/37032358 http://dx.doi.org/10.1186/s12943-023-01767-1

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