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Rebalancing SMAD7/SMAD3 Signaling Reduces Adhesion Formation during Flexor Tendon Healing

Transforming growth factor-β is a key factor in regulating adhesion formation during tendon healing. We investigated the effectiveness of SMAD family members, SMAD7 and SMAD3, in the TGF-β/Smad signaling during flexor tendon repair. Mouse flexor toe deep tendon rupture anastomosis models were made....

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Detalles Bibliográficos
Autores principales: Jiang, Ke, Li, Yuling, Xiang, Chao, Xiong, Yan, Jia, Jiameng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Microbiology and Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084761/
https://www.ncbi.nlm.nih.gov/pubmed/36859314
http://dx.doi.org/10.4014/jmb.2209.09033